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Investigation in Science 7
Unit 3 Genetics
Flicker Photo Credits:
Roger Carr
Earl
Unit Overview:
The study of some genetic disorders will be used to anchor the learning. Students will assume a fictional identity during this unit. Each student will be given a profile card containing the genotypes of their blood type, PTC tasting ability, and a genetic disease disorder. Students will learn about meiosis and heredity, and then research several genetic disorders. Students will couple with another student to determine the genetic make-up of an offspring. Biotechnology processes will be used. Students will conduct a DNA extraction and a microarray will be performed as a way of checking the genotypes of the offspring.
Enduring Understanding:
Genetic information can be used to predict traits passed from one generation to the next.
Indicators:
3.7.C.1 Explain the ways that genetic information is passed from parent to offspring in different organisms.
AGOPPE Research Process
A-Ask Questions
How is genetic information used to predict the traits of offspring?
What is the role of meiosis in distributing genes from parent to offspring?
How are genetic disorders passed down through families compared to the transmission of communicable disease?
Describe the following disorders: Huntington’s Dsease, Cystic Fibrosis, Sickle Cell Anemia and Achondroplasia. What are the causes (mode of inheritance), symptoms, and treatment options for each disease?
What systems of the body are affected by these diseases?
G-Gather Information
Decide which sources are best for your topic.
Identify key words and phrases.
Use text features to identify essential information from text.
Skim and scan for information that answers your question.
Verify the "worthiness" of the information.
Record relevant information--summarize and paraphrase--avoid plagiarism.
Record bibliographic information.
Online Databases and Ebooks
(click on the icons to open the database or ebook)
Websites
Cystic Fibrosis
Dolan DNA Learning Center: What is Cystic Fibrosis?
TeensHealth: Cystic Fibrosis
Starlight Starbright Children’s Foundation: Cystic Fibrosis
National Heart Lung and Blood Institute: Cystic Fibrosis
Medline Plus XPlain: Cystic Fibrosis
Cystic Fibrosis Foundation: Frequently Asked Questions
Cystic Fibrosis Foundation: Therapies for Cystic Fibrosis
Family Doctor.org: Cystic Fibrosis
Mayo Clinic: Cystic Fibrosis
MedicineNet.com: Cystic Fibrosis
Weekly Reader: Cystic Fibrosis
Sickle Cell Disease or Sickle Cell Anemia
Dolan DNA Learning Center: Sickle Cell Disease
TeensHealth: Sickle Cell Anemia
National Heart Lung and Blood Institute: Sickle Cell Anemia
MedicineNet.com: Sickle Cell Disease
National Institute of Health: Sickle Cell Anemia
Sickle Cell Information Center
Mayo Clinic: Sickle Cell Anemia
Centers for Disease Control and Prevention: Sickle Cell Disease
WebMD: Sickle Cell Disease
March of Dimes: Sickle Cell Disease
Huntington Disease or Huntington’s Disease
Health A- Z Huntington’s Disease with Video
Dolan DNA Learning Center: What is Huntington Disease?
National Institutes of Neurological Disorders and Stroke: Huntington’s Disease
Learn Genetics: Genetic Science Learning Center
Mayo Clinic: Huntington’s Disease
National Human Genome Research Institute: Learning about Huntington’s Disease
Huntington’s Disease Society of America: Stages of HD
Achondroplasia (Dwarfism)
Dolan DNA Learning Center: What is Achondroplasia?
TeensHealth: Dwarfism
March of Dimes: Achondroplasia
Children’s Hospital Boston: Achondroplasia
Little People of America: Frequently Asked Questions
Mayo Clinic: Dwarfism
Genetics Home Reference: Achondroplasia
No Bigger Than A Minute
Medicinet.Com: Achondroplasia
AcondroplasiaUK
Hemophilia
Dolan DNA Learning Center: What is Hemophilia?
TeensHealth: Hemophilia
National Heart Lung and Blood Institute: Hemophilia
Mayo Clinic: Hemophilia
X-Linked Inheritance: Hemophilia
Education.com
MedicineNet.com: Hemophilia
WebMD: Hemophilia
Centers for Disease Control and Prevention: Hemophilia
Tay-Sachs disease
Dolan DNA Learning Center: Tay-Sachs Disease
KidsHealth: Tay-Sachs Disease
National Institute of Neuological Disorders and Stroke
National Tay-Sachs and Allied Diseases
Google Books: Tay-Sachs Disease (Scroll down below the cover photo)
Genetics Home Reference: Tay-Sachs Disease
March of Dimes: Tay-Sachs Disease
Education.com
Albinism
TeensHealth: Understanding Albinism
NOAH: The National Organization of Albinism and Hypopigmentation
MayoClinic: Albinism
PubMed Health: Albinism
American Association for Pediatric Ophthalmology and Strabismus
Encyclopedia of Children’s Health: Albinism
Polydactyl
Children’s Hospital Boston: Polydactyl
Education.com
U.S. National Library of Medicine and NIH MedLine Plus
American Society for Surgery of the Hand
Penn Medicine Health Encyclopedia: Polydactyl
Pediatric Plastic Surgery
Encyclopedia of Children’s Health
O-Organize Information
***Use your DISEASE RESEARCH CAPTURE SHEETS to organize your findings.
Use Noodle Tools for your Works Cited Page, You must use at least 3 credible sources.

P-Present Information
You will present your findings to the class in a 5 minute presentation. Presentation (if in power point, presentation printed as hand outs) Include a picture if possible
P-Present Information
Student couples will group with another couple, who will be playing the role of genetic counselors. Genetic counselors will consult with the couple, gather information about their genotypes and phenotypes and then create a Genetic Counselor’s report. The students then switch roles, with the counselors becoming the parents and vice versa.
E-Evaluate, Assess, Reflect

Flickr photo by udt007US
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